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Brown-Colored Malignant Pleural Fluid With High Bilirubin Levels: A Case Series

Nai-Chien Huan1, Larry Ellee Nyanti1,2, Xin Ying Lee1,3

  • 1Department of Respiratory Medicine, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia.

Case Reports in Pulmonology
|November 28, 2024
PubMed
Summary

Malignant pleural effusions can appear brown due to high bilirubin levels, even without direct bile duct connection. This rare finding in adenocarcinoma patients suggests novel mechanisms for bile accumulation in the pleural space.

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Pleural Effusion I: Introduction01:25

Pleural Effusion I: Introduction

Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
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Pleural Effusion II: Symptoms and Management01:28

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Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
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