Aphthous-Like Lesions in a Patient Across Two Courses of COVID-19 Infection: A Case Report

Numerous changes in the oral cavity have been associated with COVID-19 infection, including the appearance of aphthous-like lesions. However, the precise relationship between COVID-19 and aphthous-like lesions remains unclear and poorly explained. We present the case of a 34-year-old man with no prior medical conditions who developed aphthous-like lesions three days after the onset of the COVID-19 infection. Remarkably, the patient had experienced similar aphthous-like lesions two years earlier, also within the first three days of COVID-19 infection. He had no history of aphthous-like lesions before or between these two mild courses of COVID-19 infection. The patient was treated with corticosteroids and antiseptics, resulting in the complete resolution of the oral lesions. Given the limited evidence currently available, this case report highlights a potential direct association between COVID-19 infection and the development of aphthous-like lesions.