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Updated: Jun 6, 2025

Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
COMPLETE HEART BLOCK IN PATIENTS PRESENTING WITH ACUTE ANTERIOR WALL MYOCARDIAL INFARCTION
Muhammad Ali Khan1, Kinza Sammar2, Raisa Naz3
1Department of Cardiology, Ayub Medical College Abbottabad, Pakistan.
Insights
Complete heart block (CHB) occurred in 3.3% of patients with acute anterior wall myocardial infarction (AWMI). This finding suggests extensive myocardial damage and increased mortality risk in AWMI patients with CHB.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Complete heart block (CHB) is a known complication of acute myocardial infarction (AMI).
- Limited data exists on CHB incidence and outcomes in ST-segment elevation myocardial infarction (STEMI).
- CHB in STEMI indicates widespread myocardial injury and is linked to higher sudden cardiac death risk.
Purpose of the Study:
- To determine the frequency of complete heart block (CHB) in patients presenting with acute anterior wall myocardial infarction (AWMI).
Main Methods:
- A descriptive study was conducted from February to July 2020.
- Included 244 patients aged 20-80 years with acute anterior wall ST-segment elevation myocardial infarction (AWMI).
Main Results:
- The study included 244 patients (65.6% male, 34.4% female), mean age 55.98 years.
- Complete heart block (CHB) was observed in 8 patients (3.3%).
- The majority (96.7%) of patients did not develop CHB associated with AWMI.
Conclusions:
- High incidence of heart block in AWMI suggests extensive infarction and tissue damage.
- This extensive damage can lead to increased mortality due to complete cardiac failure.
- Inferior wall MI and right ventricular infarction are associated with increased mortality risk.
Background:
Complete heart block (CHB) is a relatively common complication in post-acute myocardial infarction (AMI) patients. Data on the incidence and consequences of CHB in patients with ST-segment elevation myocardial infarction (STEMI) are limited. Besides serving as an indicator of widespread myocardial injury, the development of CHB in STEMI is also associated with a higher risk of sudden cardiac death. Although there has been an observed increase in the incidence of CHB complicating STEMI over the past few decades, attributed to improved reporting and timely diagnosis, the absolute or true incidence of CHB in STEMI patients receiving current management is underestimated. The present study aimed to determine the frequency of complete heart block in patients presenting with acute anterior wall myocardial infarction (AWMI).
Methods:
This was a descriptive study conducted in the Cardiology Department of Ayub Teaching Hospital, Abbottabad, from February to July 2020. All patients (N=244) presenting with acute Anterior Wall ST-segment elevation Myocardial Infarction were included, with ages ranging from 20 to 80 years and both genders (males and females) considered.
Results:
The mean age of the patients was 55.98±12.224, ranging from 20 to 80 years, out of a total of 244 patients. In terms of gender distribution, there were 160 (65.6%) males and 84 (34.4%) females. Regarding the frequency of smokers, 63 (25.8%) were smokers, and 181 (74.2%) were non-smokers. The frequency of complete heart block was 8 (3.3%), while 236 (96.7%) did not have acute anterior wall myocardial infarction-associated heart block.
Conclusions:
Patients admitted with inferior wall MI and right ventricular (RV) infarction were at an increased risk of mortality. The high incidence of heart block in AWMI suggests that underlying infarction and tissue damage may be extensive, leading to increased mortality secondary to complete cardiac failure.
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