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Electric stimulation: a versatile manipulation technique mediated microbial applications.

Manjila Adhikari1, Li Wang2, Dhurba Adhikari3

  • 1Department of Biomedical Engineering, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, 430074, China.

Bioprocess and Biosystems Engineering
|November 29, 2024
PubMed
Summary
This summary is machine-generated.

Electric stimulation (ES) offers precise control over microorganisms for bioremediation and biosynthesis. This review explores ES advancements and microbial applications, focusing on enhanced extracellular polymer production.

Keywords:
Electric stimulationElectroporationExtracellular polymersManipulationMicroorganisms

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Area of Science:

  • Microbial biotechnology and synthetic biology
  • Bioengineering and bioprocess engineering

Background:

  • Electric stimulation (ES) is a technique for manipulating individual microorganisms using electric fields.
  • ES applications have evolved from bioremediation to precise microbial motion control over decades.
  • Limited information exists on ES mechanisms, advancements, and diverse microbial applications, particularly in extracellular polymer production.

Purpose of the Study:

  • To review recent advancements in electric stimulation (ES) for microbial manipulation.
  • To discuss ES as a unique external manipulation technique for microorganisms.
  • To highlight ES applications in bioremediation, industry, biofilm deactivation, disinfection, and controlled biosynthesis, with a focus on extracellular polymer production.

Main Methods:

  • Comprehensive review of recent scientific literature on electric stimulation (ES) and microbial manipulation.
  • Analysis of ES mechanisms and capabilities in controlling microbial behavior and biosynthesis.
  • Exploration of specific applications, including the biosynthesis and organization of extracellular polymers.

Main Results:

  • ES enables precise manipulation and control of microorganisms for various biotechnological applications.
  • ES facilitates the extracellular biosynthesis, regulation, and organization of polymers like bacterial cellulose and microbial nanowires.
  • Recent advancements expand ES capabilities for enhanced microbial applications and bio-based product development.

Conclusions:

  • Electric stimulation (ES) is a powerful tool for engineering, manipulating, and controlling microorganisms.
  • ES offers a platform for microbial biotechnologists and synthetic biologists to develop novel bio-based applications.
  • Harnessing ES potential can lead to the production of extracellular polymers with enhanced properties and other advanced bio-products.