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Navigating Treatment-Induced Head and Neck Malignancies in Cancer Survivors
Fábio Muradás Girardi1, Gustavo Guthmann Pesenatto2, Larissa Dill Fuchs3
1Head and Neck Surgery Department, Ana Nery Hospital, Santa Cruz do Sul, Rio Grande do Sul, Brazil.
Abstract:
Cancer presents a significant global health burden. Traditional treatment modalities, especially radiotherapy and chemotherapy, have improved survival, but they have long-term consequences. Treatment-induced malignancies, a growing concern, pose risks to survivors. Often with limited treatment options, these tumors tend to have a worse survival rate. A thorough understanding of the main risk groups is critical for lifelong follow-up and personalized care strategies. This review provides an update on the knowledge of treatment-induced malignancies of the head and neck in cancer survivors; specifically, it discusses the risks, histological considerations, diagnosis and treatment strategies, follow-up recommendations, and future perspectives.
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