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Updated: Jun 6, 2025

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
A Case Report of an Osteolytic Mass Hiding Behind an Undiagnosed Parathyroid Adenoma
Mohammed S Al Olaimat1, Fahad S Al Qooz1, Zaid R Alzoubi1
1Maxillofacial Surgery, King Hussein Medical Center, Amman, JOR.
Abstract:
Hyperparathyroidism is a common endocrinopathy classified into three subtypes: primary, secondary, and tertiary. One of the rare symptoms that patients with hyperparathyroidism present is the formation of osteolytic lesions of the jaws. Brown tumors are rare skeletal osteolytic masses of a poorly understood etiology. These tumors are usually caused by a mutation in the CDC73 gene, a tumor suppressor protein gene that translates to parafibromin. Treatment has been reported to range from a conservative parathyroidectomy to resection and reconstruction. We present a case of a female who presented with a facial disfigurement for four months that was hidden under the effect of a parathyroid adenoma. Our aim is to guide the surgeon in the proper detailed management of osteolytic lesions of jaws that are related to parathyroid hyperfunction.
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