Donor-Derived Infections: A Journey From Evidence to Policy
Vivek B Beechar1, Stephanie M Pouch2, Ricardo M La Hoz1
1Division of Infectious Diseases and Geographic Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Open Forum Infectious Diseases
|December 2, 2024
Summary
Donor-derived Bartonella quintana infections are an emerging threat in organ transplantation. More research is needed to develop donor screening guidelines that prevent transmission while maximizing organ use.
Area of Science:
- Infectious Diseases
- Transplant Surgery
- Microbiology
Background:
- Donor-derived infections, particularly Bartonella quintana, are an increasing concern in solid organ transplantation.
- Bartonella quintana transmission through organ donation presents a significant risk to recipients.
Purpose of the Study:
- To highlight the emerging issue of donor-derived Bartonella quintana infection in solid organ transplantation.
- To emphasize the need for validated donor screening criteria.
Main Methods:
- Review of current literature on Bartonella quintana transmission in transplantation.
- Analysis of the impact of donor screening on organ utilization.
Main Results:
- Donor-derived Bartonella quintana infection is a growing problem in solid organ transplantation.
- Current screening protocols may not be sufficient to prevent transmission.
Conclusions:
- Validated donor screening criteria are essential to prevent Bartonella quintana transmission.
- Balancing infection prevention with organ utilization is critical for successful transplantation outcomes.
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