Related Experiment Video
Updated: Aug 7, 2026

A Pre-Clinical Porcine Model of Orthotopic Heart Transplantation
Published on: April 27, 2019
Extended Duration Bridge to Orthotopic Heart Transplant Utilizing the Impella RP Flex
Jean-Luc A Maigrot1, Ran Lee2, Andrew Higgins2
1From the Department of Thoracic and Cardiovascular Surgery, Kaufman Center for Heart Failure Treatment and Recovery, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, Ohio.
A 56-year-old man with arrhythmogenic right ventricular cardiomyopathy experienced cardiogenic shock. He was successfully bridged to heart transplantation for 29 days using the Impella RP Flex right ventricular assist device.
Area of Science:
- Cardiology
- Mechanical Circulatory Support
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) can lead to isolated right ventricular failure.
- Cardiogenic shock from right ventricular failure requires advanced support strategies.
Observation:
- A 56-year-old male patient presented with severe cardiogenic shock.
- The patient's condition was attributed to isolated right ventricular failure secondary to ARVC.
Findings:
- Successful bridging to heart transplantation was achieved using the Impella RP Flex right ventricular assist device.
- The patient received 29 days of continuous support, establishing a new longest duration record for this device.
- This case demonstrates the efficacy of the Impella RP Flex in managing acute right ventricular failure.
Implications:
- The Impella RP Flex device offers a viable option for prolonged mechanical support in severe right ventricular failure.
- This case expands the understanding of advanced therapeutic options for ARVC patients.
- Extended use of the Impella RP Flex may improve outcomes for patients awaiting heart transplantation.
More Related Videos
07:41Insertion, Maintenance, and Removal of the Percutaneous Dual Lumen Cannula Right Ventricular Assist Device
Published on: July 20, 2022
06:22Author Spotlight: Advancing Cardiovascular Research — Tailored Langendorff Perfusion Techniques for Improved Experimental Outcomes
Published on: June 14, 2024