Related Experiment Video
Updated: Jun 25, 2026

Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
Published on: November 7, 2018
[Revealing research progress for immunological characteristics of chronic hepatitis B applying single-cell RNA
1Department of Infectious Diseases, Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Institute for Viral Hepatitis, the Second Affiliated Hospital, Chongqing Medical University, Chongqing401336, China.
Abstract:
Chronic hepatitis B (CHB) is one of the major public health problems worldwide. The potential immunological mechanisms of hepatitis B virus (HBV) infection has not yet been clearly studied. Single-cell RNA sequencing (scRNA-seq) technology, as an emerging sequencing method in recent years, can provide a high-throughput view of the whole transcriptome at the single-cell level, reveal subtle changes in transcriptional profiles of immune cells during the course of chronic hepatitis B, and provide technological support for exploring the immunopathogenesis and potential therapeutic targets for CHB. This article summarizes the research progress conducted on scRNA-seq technology in order to provide novel therapeutic ideas for the immunological characteristics of chronic hepatitis B.
More Related Videos
10:25"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
Published on: February 19, 2019
10:37Analysis of HBV-Specific CD4 T-cell Responses and Identification of HLA-DR-Restricted CD4 T-Cell Epitopes Based on a Peptide Matrix
Published on: October 20, 2021