Related Experiment Video
Updated: Jun 6, 2025
Porcine Liver Transplantation Without Veno-Venous Bypass As an Extended Criteria Donor Model
Published on: August 17, 2022
CORRELATION OF PRE-TRANSPLANT MELD SCORE WITH 30- AND 60-DAYS' MORTALITY IN PATIENTS OF LIVER TRANSPLANT
Faryal Riaz Khan1, Rao Saad Ali Khan1, Khawar Shabbir1
1Pak Emirates Military Hospital, Rawalpindi-Pakistan.
Background:
The Model for End-Stage Liver Disease (MELD) score, introduced in 2002 by the United Network for Organ Sharing (UNOS), is a vital tool for predicting mortality for liver transplant candidates. Comprising serum creatinine, serum bilirubin, and international normalized ratio (INR), the MELD score includes kidney, liver, and coagulation pathway function, providing a comprehensive prognostic tool. Recent studies suggest broader prognostic implications, extending beyond organ allocation. Despite its benefits, around 15-20% of patients may not experience accurate survival predictions.
Methods:
This retrospective single-center study, covering January 2016 to September 2023 with 87 patients, explores the correlation between pre-transplant MELD scores and 30 to 60-day post-transplant survival.
Results:
Our analysis reveals no significant impact of MELD scores on survival during this period, challenging existing literature (p=0.068). The study underscores the need for nuanced risk assessment beyond MELD scores, considering diverse clinical scenarios and patient-specific variables.
Conclusions:
Our findings contribute to refining predictive models and advocate for larger-scale investigations, emphasizing a holistic approach to optimize liver transplantation outcomes.
