The Systematic Multi-domain Alzheimer's Risk Reduction Trial (SMARRT) intervention: A personalized approach to...

Area of Science:

• Gerontology
• Neuroscience
• Public Health

Background:

• Modifiable risk factors like physical inactivity and social isolation may reduce Alzheimer's disease (AD) and dementia risk.
• Understanding individual willingness and preferences for addressing these risk factors is crucial for effective interventions.

Purpose of the Study:

• To examine and describe the behavior change goals established by participants in the Systematic Multi-domain Alzheimer's Risk Reduction Trial (SMARRT).

Main Methods:

• The SMARRT trial involved older adults working with health coaches and nurses over two years to set personalized, incremental goals for dementia risk reduction.
• Quantitative analysis summarized goal numbers per risk factor, while qualitative content analysis of notes described goal types and effective strategies.

Main Results:

• Participants (n=82, aged 70-89) most frequently targeted physical activity (95%), hypertension (72%), and cognitive activity (60%) for risk reduction.
• Participants reported that health coach/nurse support, accountability, setting small goals, and managing setbacks were highly effective strategies.

Conclusions:

• Older adults at increased dementia risk, with support, establish diverse goals for risk reduction.
• A personalized, flexible strategy focusing on feasible goals and setback management offers a valuable framework for dementia risk reduction.