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Prescription versus over-the-counter venotonics: HPLC-DAD and static digestive model simulation comparison

Robert Novotny1, Matyas Orsak2, Jaromir Lachman2

  • 1Transplantation Surgery Department, Institute for Clinical and Experimental Medicine, Prague, Czech Republic - novr@ikem.cz.

International Angiology : a Journal of the International Union of Angiology
|December 3, 2024
PubMed
Summary

Prescription and over-the-counter venotonics containing diosmin and hesperidin meet declared amounts. Digestion simulation showed similar solubility and behavior for both types of venotonics, with active substances only determinable after alkalization.

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