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Updated: Jun 6, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
High-Risk Melanoma: Stage Before Operating
Stanislau Makaranka1, Zon Oo1, Jonathan Pollock1
1Department of Plastic Surgery, Nottingham University Hospitals NHS FT, Nottingham, UK.
Abstract:
Current NICE guidelines state that in high-risk melanoma patients, imaging should not be offered before SLNB unless lymph node or distant metastases are suspected. Our experience has been that in patients with pT3b, pT4a and pT4b melanomas, the rate of management-changing findings on axial imaging prior to SLNB was high and that 'stage before operating' is a better approach. We now offer full axial imaging as staging to all high-risk melanoma patients prior to SLNB and advise other skin cancer MDTs to follow this approach.

