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Prognosis in treated hypertension.

M Strate, K Thygesen, C Ringsted

    Acta Medica Scandinavica
    |January 1, 1986
    PubMed
    Summary
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    Antihypertensive treatment may not fully close the survival gap for all patients with high blood pressure. While early-stage hypertension showed similar survival to the general population, advanced stages with organ damage still had reduced survival rates.

    Area of Science:

    • Cardiology
    • Public Health
    • Hypertension Research

    Background:

    • Arterial hypertension is a significant global health concern.
    • A survival gap exists between hypertensive patients and the general population.
    • The impact of antihypertensive treatment on this survival gap requires further elucidation.

    Purpose of the Study:

    • To quantify the extent to which antihypertensive treatment reduces the survival gap in patients with arterial hypertension.
    • To compare the 10-year survival rates of treated hypertensive outpatients with a matched general population.
    • To identify factors influencing survival disparities in hypertensive individuals.

    Main Methods:

    • Actuarial methods were used to assess 10-year survival in 673 outpatients treated for arterial hypertension.

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  • Survival data were compared with expected survival derived from Danish population life tables.
  • Patients were stratified by hypertension WHO stage and presence of organ involvement.

    • Main Results:

    • In WHO stage I primary hypertension, survival rates were comparable to the background population.
    • Antihypertensive treatment did not eliminate the survival gap in WHO stage III or renal hypertension with severe organ involvement.
    • Survival decreased with increasing age but did not differ by sex or body mass index.
    • Myocardial infarction was the leading cause of death, followed by other cardiovascular events.

    Conclusions:

    • Antihypertensive treatment may normalize survival in early-stage primary hypertension but is insufficient for advanced disease with organ damage.
    • Age remains a critical factor influencing survival in hypertensive patients.
    • Further research is needed to address survival disparities in severe arterial hypertension.