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Published on: March 25, 2022
Hepato-pancreato-biliary tuberculosis: A review.
Peeyush Varshney1, Vinay Kumar Kapoor2
1Department of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.
Hepato-pancreato-biliary tuberculosis (HPB TB) is a rare condition mimicking cancer. Early diagnosis and anti-tubercular therapy (ATT) are crucial for a cure, though it
Area of Science:
- Hepatology
- Gastroenterology
- Infectious Diseases
Background:
- Hepato-pancreato-biliary (HPB) tuberculosis (TB) is an uncommon manifestation of extrapulmonary TB.
- It frequently mimics malignancy, presenting a diagnostic challenge.
Purpose of the Study:
- To review the clinical presentation, diagnostic modalities, and management of HPB TB.
- To emphasize the importance of high suspicion for pre-operative diagnosis and treatment.
Main Methods:
- A literature search of Medline/PubMed was conducted using keywords related to HPB and tuberculosis.
- Data on symptoms, imaging, and diagnostic tests were gathered and analyzed.
Main Results:
- HPB TB presents with symptoms like jaundice, weight loss, and abdominal pain, often indistinguishable from cancer.
- Imaging may show biliary dilation, mass lesions, or enlarged lymph nodes.
- Diagnosis is confirmed via biopsy, AFB staining, or molecular testing.
Conclusions:
- Prompt diagnosis of HPB TB is essential, as it is curable with anti-tubercular therapy (ATT).
- While surgery is reserved for refractory cases, most patients benefit from medical management.
- A high index of suspicion and targeted investigations can facilitate pre-operative diagnosis and appropriate treatment.
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