Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pathophysiology of Heart Failure01:17

Pathophysiology of Heart Failure

1.5K
Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
1.5K
Acute Respiratory Failure-IV01:23

Acute Respiratory Failure-IV

126
Respiratory failure can manifest suddenly or gradually, characterized by a rapid decline in PaO2 and a rapid rise in PaCO2. This situation indicates a severe respiratory problem that may quickly become a life-threatening emergency. One of the early signs of hypoxemic Acute Respiratory Failure (ARF) is a change in mental status due to the brain's sensitivity to oxygen levels and changes in acid-base balance. Symptoms such as restlessness, confusion, and agitation suggest inadequate oxygen...
126
Acute Respiratory Failure-III01:30

Acute Respiratory Failure-III

158
Hypercapnic respiratory failure, also known as Type 2 or ventilatory respiratory failure, is a severe condition characterized by the body's inability to effectively remove carbon dioxide (CO2) from the bloodstream. It leads to an arterial CO2 pressure (PaCO2) exceeding 45 mmHg and a blood pH above 7.35. This situation indicates that the body's ventilatory demand, or the ventilation needed to maintain normal PaCO2 levels, surpasses its supply or the maximum gas flow achievable without...
158
Mechanism of Cardiac Arrhythmias01:28

Mechanism of Cardiac Arrhythmias

889
Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
889
Factors Influencing Heart Rate01:30

Factors Influencing Heart Rate

2.4K
The heart rate, or pulse rate, is a vital indicator of cardiovascular health. It reflects the number of times the heart beats per minute. Various physiological and environmental factors influence heart rate, increasing or decreasing cardiac output. Understanding these factors is crucial for assessing heart function and identifying potential health issues.
Let us explore the significant factors affecting heart rate, including age, body temperature, posture, acute pain, chemical influences,...
2.4K
Disturbances in Heart Rhythm01:28

Disturbances in Heart Rhythm

904
Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow...
904

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Variability in Vasoactive Medication use Across Pediatric Intensive Care Units: A PICU Data Collaborative Study, 2010-2022.

Journal of intensive care medicine·2026
Same author

ICU UNITED: A Scalable Model for Cross-Unit Simulation in Critical Care.

Chest·2026
Same author

Extracorporeal membrane oxygenation, acute kidney injury, fluid balance, and continuous renal replacement therapy: Acute Disease Quality Initiative (ADQI) and Extracorporeal Life Support Organization (ELSO) joint consensus conference.

Intensive care medicine·2026
Same author

Factors Associated With R01 Submission Among Pediatric Critical Care Medicine Career Development Award Recipients.

Critical care medicine·2026
Same author

Double-Crossed After Vascular Ring Surgery: How One Diagnosis Literally Shifted to Another.

JACC. Case reports·2026
Same author

Single Ventricle Physiology May Not Preclude Cardiac Repair in the Setting of Congenital Diaphragmatic Hernia.

World journal for pediatric & congenital heart surgery·2026
Same journal

Drug Administration Patterns in Patients on Extracorporeal Membrane Oxygenation.

Journal of pediatric intensive care·2026
Same journal

Post-Intensive Care Syndrome in a Cohort of School-Aged Children and Adolescent ICU Survivors: The Importance of Follow-up in the Acute Recovery Phase.

Journal of pediatric intensive care·2025
Same journal

Retraction Note: The Effects of Quran Recitation on Sedation and Pain in Children.

Journal of pediatric intensive care·2024
Same journal

Severe Traumatic Brain Injury in French-Speaking Pediatric Intensive Care Units: Study of Practices.

Journal of pediatric intensive care·2024
Same journal

Simulation-Facilitated Education for Pediatric Critical Care Nurse Practitioners' Airway Management Skills: A 10-Year Experience.

Journal of pediatric intensive care·2024
Same journal

A Meta-analysis of the Utility of Red Cell Distribution Width as a Biomarker to Predict Outcomes in Pediatric Illness (PROSPERO CRD42020208777).

Journal of pediatric intensive care·2024
See all related articles

Related Experiment Video

Updated: Jun 5, 2025

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

2.1K

Factors Associated with Pediatric In-Hospital Recurrent Cardiac Arrest.

Stephanie R Brown1,2, Joan S Roberts3,4, Elizabeth Y Killien3,4

  • 1Division of Pediatric Critical Care Medicine, Oklahoma Children's Hospital, Oklahoma City, Oklahoma, United States.

Journal of Pediatric Intensive Care
|December 4, 2024
PubMed
Summary
This summary is machine-generated.

Identifying factors for recurrent cardiac arrest in children is crucial. Older age, acidosis, and organ dysfunction increase early arrest risk, while neonatal factors may reduce late arrest risk.

Keywords:
cardiac arrestextracorporeal life supportinpatientsresuscitation

More Related Videos

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
05:36

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Published on: January 30, 2020

7.6K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

721

Related Experiment Videos

Last Updated: Jun 5, 2025

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research
03:13

Technical Refinement of a Bilateral Renal Ischemia-Reperfusion Mouse Model for Acute Kidney Injury Research

Published on: November 3, 2023

2.1K
Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine
05:36

Standardized Model of Ventricular Fibrillation and Advanced Cardiac Life Support in Swine

Published on: January 30, 2020

7.6K
Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model
04:55

Author Spotlight: Simulating Pediatric Cardiac Surgery Using a Neonatal Piglet Model

Published on: May 26, 2023

721

Area of Science:

  • Pediatric critical care medicine
  • Cardiovascular research
  • Clinical epidemiology

Background:

  • In-hospital cardiac arrest (IHCA) in children can lead to recurrent events.
  • Understanding risk factors for early (<48 hours) and late (≥48 hours) recurrent arrest is vital for improving outcomes.
  • Previous research has not fully elucidated specific predictors in pediatric populations.

Purpose of the Study:

  • To identify demographic and clinical factors associated with early and late recurrent arrest in pediatric inpatients after an initial IHCA.
  • To provide insights for targeted interventions to prevent recurrent cardiac arrest (RA).

Main Methods:

  • Retrospective cohort study of pediatric inpatients (<18 years) who experienced IHCA.
  • Data collected from Seattle Children's Hospital between February 1, 2012, and September 18, 2019.
  • Analysis of factors associated with early RA (<48 hours) and late RA (≥48 hours) using logistic regression.

Main Results:

  • Older age and severe pre-arrest acidosis were linked to higher risk of early RA.
  • Pre-arrest organ dysfunction, including respiratory issues and higher PELOD2 scores, also increased early RA risk.
  • Neonatal illness category was associated with lower risk of late RA, while severe post-arrest acidosis increased late RA risk.

Conclusions:

  • Specific demographic and clinical factors can help identify pediatric patients at risk for recurrent cardiac arrest.
  • Early identification allows for potential interventions to prevent recurrent events, particularly early RA.
  • Further research can refine predictive models for personalized patient management post-IHCA.