Peripheral Arterial Disease Management: Insights From the SerbVasc Registry

Area of Science:

• Vascular Surgery
• Public Health
• Epidemiology

Background:

• Peripheral artery disease (PAD) management varies globally, necessitating region-specific data.
• The VASCUNET (Vascular Network) collaboration collects data on vascular procedures.
• Understanding PAD treatment in Serbia provides insights for similar healthcare systems.

Purpose of the Study:

• To analyze Peripheral Artery Disease (PAD) treatment data from Serbia within the VASCUNET collaboration.
• To investigate sex differences, revascularization methods, and patient outcomes in PAD management.
• To identify risk factors and predictors of morbidity and mortality in PAD patients.

Main Methods:

• Analysis of data from 1681 PAD patients across 27 Serbian hospitals (SerbVasc registry).
• Focus on sex disparities, diabetes prevalence, smoking history, and previous interventions.
• Evaluation of complication rates, in-hospital mortality, and amputation outcomes.

Main Results:

• Males constituted 69.5% of patients and were more likely to receive open surgical treatment.
• Diabetes (40.2%) and smoking (61.9%) were prevalent, significantly influencing disease progression and complications.
• In-hospital mortality was 1.6%, predicted by urgent procedures and recent myocardial infarction; revascularization with minor amputations lowered major amputation rates.

Conclusions:

• SerbVasc data offers a comprehensive view of PAD management in Serbia, highlighting significant impacts of diabetes and smoking.
• Findings underscore the need to address sex disparities and optimize treatment strategies, including the combined approach for amputations.
• The study provides valuable data for improving PAD patient outcomes in Serbia and comparable healthcare settings.