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Protocol for whole-cell patch-clamp assay for HBV-mediated sodium influx in THP-1 macrophages

Yingbao Tan1, Penghui Chen2, Xiaojuan Xin3

  • 1Department of Immunology, Army Medical University, Chongqing 400038, P.R. China.

STAR Protocols
|December 4, 2024
PubMed

Keywords:
BiophysicsCell BiologyCell cultureCell-based AssaysImmunology

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Many fundamental cell functions such as muscle contraction and nerve transmission rely on the electrical signals produced by the movement of positively and negatively charged ions across the cell membrane. One competent method to record current flowing across the whole cell or single ion channel is the patch-clamp technique.
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