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Host-in-Host Complexation: Activating Classical Hosts through Complete Encapsulation within an M9L6 Coordination Cage
Kenta Iizuka1, Hiroki Takezawa1, Makoto Fujita2,3
1Department of Applied Chemistry, School of Engineering, The University of Tokyo, Mitsui Link Lab Kashiwanoha 1, FS CREATION, 6-6-2 Kashiwanoha, Kashiwa, Chiba 277-0882, Japan.
Abstract:
This study reports a method for enhancing the functions and properties of traditional organic macrocyclic hosts by fully encapsulating them within a large M9L6 cage to form host-in-host complexes. Within the cage host, the macrocyclic organic hosts with electron-rich aromatic rings, such as cyclotriveratrylene and calix[8]arene, adopt specific orientations enhancing their inherent molecular recognition abilities. Due to the high crystallinity of the M9L6 cage, the guest encapsulation behavior of the host-in-host complexes can be observed by X-ray structural analysis.
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