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Updated: Jun 5, 2025

Whole-Body Nanoparticle Aerosol Inhalation Exposures
Published on: May 7, 2013
Occupational Exposure to Inhalable Agents Is Associated With Reduced Work Ability: A Prospective Cohort Study in
Geir Klepaker1, Kjell Torén, Paul Keefer Henneberger
1From the Department of Occupational and Environmental Medicine, Telemark Hospital, Skien, Norway (G.K., A.K.M.F.); Department of Occupational and Environmental Medicine/Department of Public Health and Community Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden (K.T.); Respiratory Health Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, WV (P.K.H.); and Institute of Clinical Medicine (J.K.) and Department of Community Medicine and Global Health, Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway (A.K.M.F.).
Background:
This study aimed to assess Work Ability Score (WAS) in 2018 based on self-reported data regarding inhalable occupational exposure and data from a Northern European Job-Exposure Matrix recorded in 2013.
Methods:
During the 5-year follow-up period of this population-based study, 4423 participants completed a postal questionnaire comprising self-reported questions regarding occupational exposure, work history, and WAS.
Results:
Ever, weekly, and daily exposure to vapors, gas, dust, and fumes in the last 5 years in 2013 was associated with reduced WAS in 2018. The Northern European Job-Exposure Matrix data showed that exposure to irritants, wood and paper dust, and mixed agricultural agents was associated with reduced WAS.
Conclusions:
Exposure to several occupational inhalable substances is associated with reduced work ability. We recommend reducing inhalable occupational exposure to prevent reduced work ability.
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