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Updated: Jun 5, 2025
06:15
Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
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Adult-Onset Acquired Ichthyosis Revealing an Underlying Colon Adenocarcinoma
Maria El Gemayel1, Tatiana Hawat2, Brian A Cahn3
1Gastroenterology and Hepatology, University of Illinois Chicago, Chicago, USA.
Cureus
|December 6, 2024
Summary
Acquired ichthyosis in adults can signal underlying cancer. This case links ichthyosis to colon adenocarcinoma, stressing the need for malignancy screening in such patients.
Area of Science:
- Dermatology
- Oncology
Background:
- Acquired ichthyosis is a rare adult-onset skin condition.
- It is frequently linked to systemic diseases, notably cancers.
Observation:
- A 38-year-old male presented with widespread, fish-like scaling on his trunk and limb extensors.
- Standard treatments for ichthyosis were ineffective.
- A biopsy confirmed acquired ichthyosis, and imaging detected colon adenocarcinoma.
Findings:
- The patient had a family history of colon cancer, suggesting a possible genetic link.
- Acquired ichthyosis served as a paraneoplastic marker for colon adenocarcinoma.
Implications:
- Diagnosis of acquired ichthyosis necessitates thorough investigation for underlying malignancies.
- Early detection of associated cancers, especially with a family history, is crucial.
- This case emphasizes acquired ichthyosis as a potential indicator for prompt cancer management.
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