Related Experiment Video
Updated: Jun 5, 2025

12:31
A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
15.1K
Sequence-selective pulldown of recognition-encoded melamine oligomers using covalent capture on a solid support
Luis Escobar1, Daniel Sun1, Mohit Dhiman1
1Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK. herchelsmith.orgchem@ch.cam.ac.uk.
Abstract:
The covalent capture of recognition-encoded melamine oligomers (REMO) with a target attached to a solid support was investigated. Sequence-selective pulldown of complementary oligomers was observed when the target was challenged with a randomised library of oligomers. The approach provides an affinity selection method for the discovery of functional REMO sequences.

