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Updated: Jun 5, 2025

Bone Marrow Transplantation Procedures in Mice to Study Clonal Hematopoiesis
Published on: May 26, 2021
Preventing radiation and chemo toxicity: Insights from bone marrow-on-a-chip
1Institute of Biomedical Engineering, University of Toronto, 164 College St., Toronto, ON, Canada; Department of Chemical Engineering & Applied Chemistry, University of Toronto, 200 College St., Toronto, ON, Canada; Toronto General Hospital Research Institute, University Health Network, 200 Elizabeth St., Toronto, ON, Canada; Terrence Donnelly Centre for Cellular & Biomolecular Research, University of Toronto, 160 College St., Toronto, ON, Canada.
None:
Species-specific differences motivate the development of human hematopoiesis models. Georgescu et al.1 present a microfluidic model of the human bone marrow perivascular niche to capture innate immune cell mobilization. Automated cultivation and high-content analysis for robust insights enabled studies of radiation injury and chemotherapy dosing.
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