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Updated: Jun 5, 2025

Modification and Functionalization of the Guanidine Group by Tailor-made Precursors
Published on: April 27, 2017
Ethyl (2RS,3SR,4RS)-1-ethyl-2-(furan-2-yl)-4-hy-droxy-5-oxopyrrolidine-3-carboxyl-ate
Nor Habibah Mohd Rosli1, Mohd Fazli Mohammat2, Mohd Abdul Fatah Abdul Manan3
1Faculty of Applied Sciences Universiti Teknologi MARA (UiTM) Pahang Jengka Campus 26400 Bandar Tun Abdul Razak Jengka Pahang Malaysia.
Abstract:
The title racemic oxopyrrolidine compound, C13H17NO5, contains three stereogenic centres and crystallizes with two mol-ecules in the asymmetric unit. The five-membered pyrrolidine rings in both mol-ecules exhibit envelope conformations. The N-ethyl group of one of the mol-ecules is disordered over two sets of sites in a 0.836 (4):0.164 (4) ratio. In the crystal, both mol-ecules form inversion dimers through pairwise O-H⋯O hydrogen bonds, generating R 2 2(10) loops, which are linked into a three-dimensional network by weak C-H⋯O hydrogen bonds.
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