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Microstate and Omega Complexity Analyses of the Resting-state Electroencephalography
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Resting-State EEG Microstates Dynamics Associated with Interindividual Vulnerability to Sleep Deprivation
Zehui Liu1, Tian Xie1, Ning Ma1
1Philosophy and Social Science Laboratory of Reading and Development in Children and Adolescents (South China Normal University), Ministry of Education; Center for Sleep Research, Center for Studies of Psychological Application, Guangdong Key Laboratory of Mental Health & Cognitive Science, School of Psychology, South China Normal University, Guangzhou, 510631, People's Republic of China.
Nature and Science of Sleep
|December 10, 2024
Summary
Sleep deprivation alters brain network dynamics, affecting EEG microstates. Individual differences in these microstate changes explain varying vulnerability to sleep loss.
Area of Science:
- Neuroscience
- Sleep Research
- Brain Dynamics
Background:
- Sleep deprivation impairs cognitive functions, particularly vigilance.
- Large-scale brain network dynamics are affected by sleep loss.
- Interindividual differences in vulnerability to sleep deprivation are not well understood.
Purpose of the Study:
- To investigate the effects of sleep deprivation on resting-state brain activity using EEG microstate analysis.
- To explore how sleep deprivation differentially affects brain networks across individuals.
Main Methods:
- 44 healthy adults underwent baseline sleep and 24-hour sleep deprivation.
- Resting-state EEG was recorded, and microstate analysis was performed.
- Participants were classified as vulnerable or resilient based on psychomotor vigilance task performance changes.
Main Results:
- Sleep deprivation altered microstate occurrences (decreased A, B, D; increased C) and transition probabilities.
- Vulnerable individuals showed reduced microstate B occurrence and altered C-to-B transitions post-deprivation.
- Resilient individuals did not exhibit these specific microstate changes.
Conclusions:
- Sleep deprivation significantly impacts dynamic brain-state properties.
- Interindividual differences in EEG microstate dynamics may underlie vulnerability to sleep deprivation.
- Microstate analysis offers insights into the neural basis of sleep deprivation effects.
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