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Updated: Jun 5, 2025
Detection of Microregional Hypoxia in Mouse Cerebral Cortex by Two-photon Imaging of Endogenous NADH Fluorescence
Published on: February 21, 2012
A ratiometric two-photon fluorescent probe for the quantification of nitroreductase in hypoxic neurons
Zhiquan Tang1, Hong Huang1, Yuanyuan Yao1
1College of Biological, Chemical Science and Engineering, Jiaxing University, Jiaxing 314001, China. huangho17@zjxu.edu.cn.
Abstract:
We developed a novel ratiometric two-photon fluorescent probe for the selective and precise detection of nitroreductase (NTR) in neurons. Using this probe, we found that hypoxic stimulation could up-regulate endogenous NTR levels.
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