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Updated: May 11, 2026
Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
Published on: November 8, 2012
Diagnostic performance of simultaneous multislice diffusion-weighted imaging in differentiating breast lesions: a
Yuqi Tan1, Zheng Ye1, Xinyang Lv1
1Department of Radiology, West China Hospital, Sichuan University, Chengdu 610041, China.
Objectives:
To investigate the diagnostic performance of simultaneous multislice diffusion-weighted imaging (SMS-DWI) in differentiating malignant and benign breast lesions, and compare it with conventional single shot and readout segmented echo planar imaging without the SMS technique.
Methods:
The literature search was performed in PubMed, Embase, and Web of Science to identify comparative studies reporting the diagnostic performance of SMS-DWI and conventional DWI in patients with breast lesions. Histopathological analysis was used as a reference standard for malignant breast lesions. The methodological quality was evaluated using QUADAS-2 scale. The summary sensitivity, summary specificity, and area under the curve (AUC) of the summarized receiver operating characteristic curve were calculated and compared between SMS-DWI and conventional DWI using a bivariate random-effects model. Heterogeneity was explored with meta-regression and subgroup analyses.
Results:
Six studies with 626 patients and 649 breast lesions (benign: 222, malignant: 427) were included. The summary sensitivity, summary specificity, and AUC for SMS-DWI were 0.89 (95% CI: 0.78-0.95), 0.94 (95% CI: 0.81-0.98), and 0.96 (95% CI: 0.94-0.98), respectively, and those for conventional DWI were 0.90 (0.95 CI: 0.84-0.94), 0.87 (95% CI: 0.80-0.92), and 0.94 (95% CI: 0.92-0.96), respectively. The diagnostic performance was not significantly different between SMS-DWI and conventional DWI (P = .337).
Conclusions:
SMS-DWI has high diagnostic performance in differentiating breast lesions, which is not significantly different from the conventional DWI.
Advances In Knowledge:
There is no significant difference between SMS-DWI and conventional DWI in differentiating breast lesions, suggesting SMS-DWI may be a potential alternative to conventional DWI in breast imaging.
