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Updated: Jun 5, 2025

A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects
Published on: May 4, 2021
[Recreational use of nitrous oxide may lead to acute complications]
1doktorand, ledningsläkare, specialist i akutsjukvård och internmedicin , Universitetssjukhuset i Linköping; institutionen för biomedicinska och kliniska vetenskaper, Linköpings universitet.
Abstract:
The use of nitrous oxide (N2O) as a recreational drug has significantly increased around the world in the last decade and has become a common occurrence in Sweden. Nitrous oxide can be easily accessed, purchased from party stores and online, and is legal in Sweden. There is a common misconception that nitrous oxide is harmless because it is used in healthcare. However, chronic nitrous oxide abuse can lead to a functional state of B12 deficiency with neurological and thromboembolic complications. The present case illustrates that recreational use of nitrous oxide may also lead to acute complications, including seizures and rupture of the airways.
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