Uropathogenic Pan-Drug-Resistant Providencia rettgeri Infection in a Patient With an Indwelling Urinary Catheter: A...

This case report details the clinical management and implications of infection with pan-drug-resistant Providencia rettgeri in a 50-year-old male admitted and diagnosed with acute peritonitis due to hollow viscus perforation, highlighting an emerging challenge in healthcare settings. Following emergency laparotomy and intensive care admission, the patient was catheterized to assist urine drainage and subsequent urine bacterial culture which yielded pan-drug-resistant P. rettgeri, signifying a notable instance of nosocomial infection by a multi-drug-resistant organism. Despite the organism's resistance to broad-spectrum antibiotics, clinical improvement was observed with levofloxacin treatment, underlining the potential discrepancy between in vitro resistance patterns and in vivo response, particularly in urinary tract infections (UTIs) where urine drug concentrations are pivotal. This case underscores the necessity for heightened surveillance, stringent infection control measures, and judicious antibiotic use in managing infections caused by pan-drug-resistant pathogens like P. rettgeri, challenging the traditional paradigms of antimicrobial resistance and therapy in hospital settings.