Association Between Sleep Quality and Cirrhotic Cardiomyopathy: A Prospective Case-Control Study

Area of Science:

• Cardiology
• Gastroenterology
• Sleep Medicine

Background:

• Cirrhotic cardiomyopathy (CCM) is a common complication in patients with liver cirrhosis.
• Understanding the risk factors for CCM is crucial for early detection and management.

Purpose of the Study:

• To evaluate changes in sleep quality in patients with cirrhotic cardiomyopathy (CCM).
• To identify clinical characteristics and risk factors associated with CCM in liver cirrhosis patients.

Main Methods:

• The study included 18-75 year old liver cirrhosis patients.
• Clinical examination results were collected to assess CCM characteristics and risk factors.
• Pittsburgh Sleep Quality Index (PSQI), Global Left Ventricular Strain (GLS), and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were analyzed.

Main Results:

• CCM onset was not linked to the etiology of cirrhosis.
• Poor sleep quality (PSQI score), low absolute GLS, and high NT-proBNP levels were identified as independent risk factors for CCM.
• Odds ratios: PSQI (13.476), GLS (0.328), NT-proBNP (1.050).

Conclusions:

• Decreased sleep quality is common in CCM patients.
• Poor sleep quality, reduced GLS, and elevated NT-proBNP may increase CCM risk in cirrhotic patients.
• Further validation with larger sample sizes is required.