Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A platelet function defect in preeclampsia.

J G Kelton, D J Hunter, P B Neame

    Obstetrics and Gynecology
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Can pain flares in knee osteoarthritis be predicted?

    Scandinavian journal of rheumatology·2021
    Same author

    Cost-effectiveness of duloxetine for knee OA subjects: the role of pain severity.

    Osteoarthritis and cartilage·2020
    Same author

    Association of weather factors with the risk of pain exacerbations in people with hip osteoarthritis.

    Scandinavian journal of rheumatology·2020
    Same author

    Is the Patient Activation Measure a valid measure of osteoarthritis self-management attitudes and capabilities? Results of a Rasch analysis.

    Health and quality of life outcomes·2020
    Same author

    Association of baseline and change in tibial and femoral cartilage thickness and development of widespread full-thickness cartilage loss in knee osteoarthritis - data from the Osteoarthritis Initiative.

    Osteoarthritis and cartilage·2020
    Same author

    A consensus-based framework for conducting and reporting osteoarthritis phenotype research.

    Arthritis research & therapy·2020
    Same journal

    The Political Determinants of Obstetric Prescribing.

    Obstetrics and gynecology·2026
    Same journal

    Glucagon-Like Peptide-1 Receptor Agonists and Risk of Adverse Maternal Pregnancy Outcomes: A Systematic Review and Meta-analysis.

    Obstetrics and gynecology·2026
    Same journal

    Milestones in Motion: Vaginal Birth After Cesarean.

    Obstetrics and gynecology·2026
    Same journal

    Ebola Virus in Pregnancy.

    Obstetrics and gynecology·2026
    Same journal

    A Quality-Improvement Study Evaluating Three Postpartum Prophylactic Oxytocin Rates and Blood Loss After Vaginal Birth.

    Obstetrics and gynecology·2026
    Same journal

    The Effects of Climate Change on Obstetric and Gynecologic Health.

    Obstetrics and gynecology·2026
    See all related articles

    Preeclampsia can cause acquired platelet function defects, impacting bleeding. These platelet issues and bleeding times often normalize after delivery in preeclamptic patients.

    Area of Science:

    • Obstetrics and Gynecology
    • Hematology
    • Perinatology

    Background:

    • Preeclampsia is a serious pregnancy complication.
    • Platelet dysfunction is a potential factor in preeclampsia-related bleeding.

    Purpose of the Study:

    • To investigate platelet function in preeclamptic patients.
    • To correlate platelet count, bleeding time, and thromboxane B2 biosynthesis.

    Main Methods:

    • Prospective study comparing 26 preeclamptic patients with 17 controls.
    • Assessed in vivo platelet function (bleeding time) and in vitro function (collagen-stimulated thromboxane B2).

    Main Results:

    • 34% of preeclamptic patients had thrombocytopenia.
    • Prolonged bleeding times were observed in both thrombocytopenic and non-thrombocytopenic patients.

    Related Experiment Videos

  • Impaired thromboxane B2 biosynthesis was linked to prolonged bleeding times in some patients.

    • Conclusions:

    • A significant subset of preeclamptic patients exhibit acquired platelet function defects.
    • These defects may contribute to bleeding complications in preeclampsia.
    • Platelet parameters and bleeding times generally normalized post-delivery.