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The Novel HLA-C*03:656 Allele Identified by Next-Generation Sequencing

Manli Shen1, Jo-Ellen Jennemann2, Patricia Willey2

  • 1Department of Pathology and Immunology, Washington University, St. Louis, Missouri, USA.

HLA
|December 12, 2024
PubMed
Abstract

Keywords:
HLANGSnovel allele

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Next-generation Sequencing03:00

Next-generation Sequencing

The first human genome sequencing project cost $2.7 billion and was declared complete in 2003, after 15 years of international cooperation and collaboration between several research teams and funding agencies. Today, with the advent of next-generation sequencing technologies, the cost and time of sequencing a human genome have dropped over 100 fold.
Next-Generation Sequencing Methods
Although all next-generation methods use different technologies, they all share a set of standard features.