Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

3.6K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
3.6K
Pneumothorax-II01:27

Pneumothorax-II

120
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
120
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

199
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
199
Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

4.2K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
4.2K
Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

303
Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
303
Endoscopic Studies I: Bronchoscopy and Thoracoscopy01:30

Endoscopic Studies I: Bronchoscopy and Thoracoscopy

173
Endoscopy is a non-surgical medical technique used to examine a person's internal organs and vessels. This lesson will focus on two types of endoscopic studies: bronchoscopy and thoracoscopy.
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
173

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An intrathyroidal cystic parathyroid adenoma localised with [<sup>18</sup>F]fluorocholine PET/CT in pregnancy.

EJNMMI reports·2026
Same author

Single-cell RNA sequencing in thyroid cancer: a methodological review and thyroid specific dissociation protocol.

Thyroid research·2026
Same author

Data Harmonization for Collaborative Research Among Australian and US Registries: A Case Study in Medullary Thyroid Cancer (MTC).

World journal of surgery·2026
Same author

Rare Association Between Neurofibromatosis Type 1 and Adrenocortical Carcinoma.

Clinical case reports·2026
Same author

A Study of Time to Recovery Following Loss of Neuromonitoring Signal of the Recurrent Laryngeal Nerve in Thyroid Surgery.

World journal of surgery·2026
Same author

Atypical morphological features in secondary and tertiary hyperparathyroidism mimic malignancy: a detailed clinicopathological study.

Pathology·2026

Related Experiment Video

Updated: Jun 5, 2025

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

25.5K

Intra-thoracic thyroid rests: an updated classification and case series.

Hazel Serrao-Brown1, Jakob Kostenbauer1, Alex Papachristos1

  • 1Endocrine Surgery Unit, University of Sydney, Royal North Shore Hospital, St Leonards, New South Wales, Australia.

ANZ Journal of Surgery
|December 12, 2024
PubMed
Summary

A new Grade V classification for completely disconnected thyroid rests is proposed. Recognizing these "forgotten goitres" is crucial to prevent recurrence after surgery.

Keywords:
intrathoracic goitresubsternal goitrethyroid rest

More Related Videos

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

3.6K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

481

Related Experiment Videos

Last Updated: Jun 5, 2025

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
10:19

Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration

Published on: November 10, 2014

25.5K
Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

3.6K
Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
03:55

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

481

Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Embryology

Background:

  • Thyroid rests are common embryological remnants with potential for pathology.
  • Existing classification (Grades I-IV) describes varying degrees of connection to the thyroid gland.
  • Proposed Grade V classification for entirely intra-thoracic, disconnected thyroid rests.

Purpose of the Study:

  • To introduce and validate the proposed Grade V classification for thyroid rests.
  • To highlight the clinical significance of recognizing and completely excising Grade V rests.
  • To emphasize the potential for recurrence of mediastinal goitres if these rests are missed.

Main Methods:

  • Retrospective review of thyroidectomy cases for benign retrosternal thyroid disease (Jan 2015 - Jan 2022).
  • Inclusion of patient demographics, pre-operative work-up, intra-operative findings, histopathology, and complications.
  • Identification and classification of thyroid rests based on their connection to the thyroid gland.

Main Results:

  • 1087 thyroidectomies performed for benign retrosternal goitre.
  • 26 Grade V rests identified in 20 patients (1.8% prevalence).
  • Surgery for Grade V rests involved sternotomy or manubriotomy, often for compressive symptoms.

Conclusions:

  • Recognition of completely disconnected thyroid rests (Grade V) is vital.
  • Tailored pre-operative assessment is necessary for effective surgical planning.
  • Incomplete excision of Grade V rests can lead to persistent or recurrent 'forgotten goitres'.