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Updated: Jun 5, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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A Graph-based Goat Pangenome Reveals Structural Variations Involved in Domestication and Adaptation

Peipei Bian1, Jiaxin Li1, Shishuo Zhou1

  • 1Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, Yangling, Shaanxi 712100, China.

Molecular Biology and Evolution
|December 12, 2024
PubMed
Summary

We created a goat pangenome and structural variation database to understand genome complexity. This resource identified novel genetic variations linked to goat domestication, immunity, and adaptation.

Keywords:
de novo assemblydomesticationgraph-based pangenomelow-coverage sequencingstructural variations

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