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[Unveiling Hormonal Secrets]

Andrés Felipe García Ramos1, Claudia Monsalve Arango2, Jose Fernando Botero Arango3

  • 1Clínica Imbanaco. Departamento de Endocrinología.

Revista De La Facultad De Ciencias Medicas (Cordoba, Argentina)
|December 13, 2024
PubMed
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Thyroid dysfunction in pregnancy poses risks to mothers and babies. Early diagnosis and management, especially for overt hypothyroidism, improve outcomes, though borderline cases require more research.

Keywords:
pregnancy complicationsprimary health carehypothyroidismthyroid gland

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Area of Science:

  • Endocrinology
  • Obstetrics
  • Reproductive Health

Background:

  • Thyroid dysfunction during pregnancy presents significant risks to both maternal and fetal health, particularly in early gestation.
  • Proactive pre-conception and conception care are vital for ensuring positive pregnancy outcomes.

Purpose of the Study:

  • To synthesize current scientific evidence on diagnosing and treating thyroid dysfunction in pregnancy.
  • To provide guidance on thyroid physiology during pregnancy and identifying high-risk individuals.

Main Methods:

  • A comprehensive bibliographic review was conducted using DeCS and MeSH terms.
  • Searched 5 databases from 2015-2022, including English and Spanish articles relevant to the PICOT question.
  • Included 32 articles after screening 1452 initial records.

Main Results:

  • Overt hypothyroidism during pregnancy is linked to adverse maternal-fetal outcomes, which are improved with treatment.
  • Evidence for treating borderline thyroid conditions like subclinical hypothyroidism and isolated hypothyroxinemia remains limited due to scarce controlled trials.

Conclusions:

  • Treatment of overt hypothyroidism in pregnancy is recommended to mitigate adverse outcomes.
  • Further research is needed for borderline thyroid conditions in pregnancy.
  • Physicians must be knowledgeable about managing thyroid conditions during gestation.