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Primary Cutaneous Rhabdoid Squamous Cell Carcinoma: A Case Report and Review of Molecular Features
Svetlana Bobkova1, Eli P Oldham2, Carlos Gomez-Meade3
1Biomedical Sciences, Oklahoma State University Center for Health Sciences, Tulsa, USA.
Cureus
|December 16, 2024
Summary
We report a rare case of aggressive rhabdoid squamous cell carcinoma (RSCC) on the scalp. This variant, characterized by specific cell morphology, presents a high risk for metastasis and poor prognosis.
Area of Science:
- Dermatopathology
- Oncology
- Rare Cancer Variants
Background:
- Rhabdoid squamous cell carcinoma (RSCC) is an aggressive variant of squamous cell carcinoma (SCC).
- Rhabdoid morphology is rare in primary cutaneous tumors, with fewer than 10 documented cases.
- This variant is characterized by specific histopathological features, including tumor cells with eccentrically located nuclei and abundant eosinophilic cytoplasm.
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