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PLUS-M Mobility Values of Osseointegration Patients: How Do Osseointegration Limb Replacement Prosthesis Users
Brian Joseph Page1, Gerard A Sheridan2, Michael D Greenstein3
1From the Hospital for Special Surgery and New York Presbyterian-Weill Cornell Medical Center, Orthopaedic Trauma Service, New York, New York.
American Journal of Physical Medicine & Rehabilitation
|December 16, 2024
Summary
Osseointegration limb replacement prosthesis users (OI-LRPU) show better functional mobility than traditional socket prosthesis users (TSPU). Younger patients at amputation also report improved outcomes with OI-LRPU.
Area of Science:
- Orthopedic Surgery
- Biomedical Engineering
- Rehabilitation Medicine
Background:
- Traditional socket prostheses present challenges in functional mobility for amputees.
- Osseointegration (OI) offers a potential alternative for limb replacement prosthesis users (LRPU).
Purpose of the Study:
- To compare functional mobility outcomes of OI-LRPU with normative data from traditional socket prosthesis users (TSPU).
- To identify patient-specific factors predicting functional mobility scores in OI-LRPU.
Main Methods:
- Retrospective review of patients who underwent osseointegration.
- 30 OI-LRPU (15 femoral, 15 tibial) completed the Prosthesis and Limb Outcome Measure (PLUS-M) survey.
- Comparison of PLUS-M scores between OI-LRPU and age/etiology-matched TSPU.
Main Results:
- OI-LRPU demonstrated significantly higher PLUS-M T-scores compared to TSPU for both above-knee (p=0.027) and below-knee (p=0.029) amputations.
- Younger patients at the time of index amputation showed significantly improved PLUS-M raw (p=0.047) and percentile scores (p=0.041).
- Tibial OI scores were marginally higher than femoral OI scores, but this difference was not statistically significant.
Conclusions:
- Osseointegration limb replacement prosthesis users (OI-LRPU) exhibit superior functional mobility outcomes compared to traditional socket prosthesis users (TSPU).
- Patient age at the time of index amputation is a significant predictor of improved functional mobility outcomes in OI-LRPU.

