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Related Concept Videos

Pulmonary Function Tests01:25

Pulmonary Function Tests

302
Pulmonary Function Tests (PFTs)
Pulmonary Function Tests are crucial diagnostic tools for assessing respiratory function, particularly in patients with chronic respiratory disorders. They comprehensively evaluate lung volumes, ventilatory function, breathing mechanics, diffusion, and gas exchange. These tests help diagnose pulmonary diseases and play a significant role in monitoring disease progression, evaluating disability, and assessing response to therapy.
PFTs involve using a spirometer, a...
302

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Differential item functioning between English, German, and Spanish PROMIS® physical function ceiling items.

Constantin Yves Plessen1, Felix Fischer2,3, Claudia Hartmann1

  • 1Center for Patient-Centered Outcomes Research, Medizinische Klinik mit Schwerpunkt für Psychosomatik, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Charitéplatz 1, 10097, Berlin, Germany.

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
|December 16, 2024
PubMed
Summary
This summary is machine-generated.

The Patient Reported Outcomes Measurement Information System (PROMIS®) Physical Function item bank is valid across Argentina, Germany, and the U.S. Differential item functioning (DIF) was negligible, supporting universal applicability of translated items.

Keywords:
Differential item functioningPROMISPhysical functionSensitivity analysis

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Area of Science:

  • Health Measurement
  • Psychometrics
  • Cross-cultural Adaptation

Background:

  • Patient-reported outcome measures (PROMs) require rigorous validation for international use.
  • The Patient Reported Outcomes Measurement Information System (PROMIS®) Physical Function item bank is a widely used tool for assessing physical functioning.
  • New items require cross-cultural validation to ensure measurement equivalence.

Purpose of the Study:

  • To evaluate the psychometric properties and cross-cultural validity of German and Spanish translations of 35 new items in the PROMIS® Physical Function item bank 2.0.
  • To assess differential item functioning (DIF) for these translated items across general population samples from Argentina, Germany, and the United States.

Main Methods:

  • Data were collected from 3601 participants (1001 Spanish, 1000 German, 1600 English) via online panels.
  • Differential item functioning (DIF) was assessed using a multiverse analysis approach within a logistic ordinal regression framework.
  • Analytic choices were systematically varied to ensure robustness of DIF identification.

Main Results:

  • Translated items generally demonstrated unidimensionality, monotonicity, and local independence.
  • A multiverse analysis identified consistent DIF in four items across languages.
  • The impact of DIF on test scores was negligible at the test level, with minimal differences observed between Argentina and the US/Germany after DIF correction.

Conclusions:

  • The PROMIS® Physical Function items demonstrate universal applicability across general populations in Argentina, Germany, and the U.S.
  • Sensitivity analyses confirmed the robustness of DIF identification across various analytical decisions.
  • Multiverse analysis offers a valuable approach for addressing challenges in DIF identification.