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Pot-Pollen Volatiles, Bioactivity, Synergism with Antibiotics, and Bibliometrics Overview, Including Direct Injection
Patricia Vit1, Maria Araque2, Bajaree Chuttong3
1Apitherapy and Bioactivity, Food Science Department, Faculty of Pharmacy and Bioanalysis, Universidad de Los Andes, Mérida 5101, Venezuela.
Foods (Basel, Switzerland)
|December 17, 2024
Summary
Stingless bee pot-pollen, a nutraceutical, shows promise in combating antimicrobial resistance by synergizing with antibiotics. Further research into its flavor and nest materials is recommended for pharmaceutical and food science applications.
Area of Science:
- Entomology and Food Science
- Microbiology and Pharmacology
Background:
- Stingless bees (Meliponini) process pollen into 'pot-pollen' in cerumen pots, distinct from 'bee bread'.
- Pot-pollen possesses significant nutraceutical properties beneficial for both bees and humans, with potential pharmaceutical applications.
Purpose of the Study:
- To explore the potential of stingless bee pot-pollen as a source of novel antimicrobial agents.
- To investigate the synergistic effects of pot-pollen extracts with antibiotics against drug-resistant bacteria.
- To analyze the scientific literature on pot-pollen and direct injection food flavor using bibliometric methods.
Main Methods:
- Ethanolic extracts of *Tetragonisca angustula* pot-pollen were tested for synergism with antibiotics against extensively drug-resistant bacteria.
- Volatile Organic Compound (VOC) richness in pot-pollen from different stingless bee species was reviewed.
- Bibliometric analysis of publications on pot-pollen and direct injection food flavor was conducted using the Scopus database and Bibliometrix-R package.
Main Results:
- Demonstrated synergism between *Tetragonisca angustula* pot-pollen extracts and antibiotics against extensively drug-resistant bacteria, highlighting potential for combating antimicrobial resistance (AMR).
- Comparative review of VOC richness across different stingless bee species was performed.
- Identified prolific authors, institutions, countries, and funding sponsors in the fields of pot-pollen and food flavor research.
Conclusions:
- Stingless bee pot-pollen exhibits potential as a novel source of anti-antimicrobial-resistant agents, offering synergistic effects with conventional antibiotics.
- Further research into the bioactivity of pot-pollen VOCs and its application in direct injection food flavor is warranted.
- The study provides scientific insight into the interaction between pot-pollen and bioanalytical techniques, encouraging joint research projects.

