Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

88
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
88

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hydrogel-Based Sensors: Compositions, Fabrication, Sensing Mechanism, and Applications.

Polymers·2026
Same author

Metal-Organic Frameworks as Room Temperature Chemiresistive Ammonia Gas Sensing Material: A Review.

Sensors (Basel, Switzerland)·2026
Same author

Sustainable Cellulose-Bentonite Composites for Wastewater Treatment.

Materials (Basel, Switzerland)·2025
Same author

Research Advances in Natural Polymers for Environmental Remediation.

Polymers·2025
Same author

Cellulose-Based Electrochemical Sensors.

Sensors (Basel, Switzerland)·2025
Same author

ASO Author Reflections: Personal Insights and Reflections on the Burden of Breast Cancer Among Adolescents and Young Adults.

Annals of surgical oncology·2025
Same journal

RETRACTED: Zhang et al. A Novel Framework for Reconstruction and Imaging of Target Scattering Centers via Wide-Angle Incidence in Radar Networks. <i>Sensors</i> 2025, <i>25</i>, 6802.

Sensors (Basel, Switzerland)·2026
Same journal

Enhancing Unsupervised Multi-Source Domain Adaptation for Person Re-Identification via Mixture of Experts and Graph-Based Relation.

Sensors (Basel, Switzerland)·2026
Same journal

Development of an Instrumented Glove for Palmar Pressure Assessment in Kayakers.

Sensors (Basel, Switzerland)·2026
Same journal

Development and Experimental Validation of an Autonomous IoT-Based Monitoring System for Real-Time Water Quality Assessment in the Amazon River.

Sensors (Basel, Switzerland)·2026
Same journal

Semi-Supervised Adversarial Learning Framework for Controller Area Network Bus Intrusion Detection.

Sensors (Basel, Switzerland)·2026
Same journal

Smart Optimization Method for Safety Signs in Innovative Manufacturing Environments Integrating Industrial Field IoT Sensors and Knowledge Graphs.

Sensors (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: May 1, 2026

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.1K

Recent Developments in Aptamer-Based Sensors for Diagnostics.

Muhammad Sheraz1, Xiao-Feng Sun1, Yongke Wang1

  • 1School of Chemistry and Chemical Engineering, Northwestern Polytechnical University, Xi'an 710072, China.

Sensors (Basel, Switzerland)
|December 17, 2024
PubMed
Summary
This summary is machine-generated.

Aptamer biosensors offer a cost-effective and sensitive solution for diagnosing non-communicable diseases (NCDs). These advanced aptasensors show great promise for point-of-care diagnostics, improving disease management globally.

Keywords:
SELEXaptamer-based biosensorschronic and non-communicable diseasespoint-of-care diagnostics

More Related Videos

Design and Development of Aptamer&#8211;Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications
08:23

Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications

Published on: June 23, 2016

12.2K
In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
12:23

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Published on: September 7, 2022

1.6K

Related Experiment Videos

Last Updated: May 1, 2026

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
12:31

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay

Published on: February 28, 2015

15.1K
Design and Development of Aptamer&#8211;Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications
08:23

Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications

Published on: June 23, 2016

12.2K
In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses
12:23

In Vitro Selection of Aptamers to Differentiate Infectious from Non-Infectious Viruses

Published on: September 7, 2022

1.6K

Area of Science:

  • Biomedical Engineering
  • Analytical Chemistry
  • Molecular Diagnostics

Background:

  • Non-communicable diseases (NCDs) represent a major global health challenge, necessitating improved diagnostic tools.
  • Traditional diagnostic methods for NCDs are often costly, slow, and require extensive infrastructure, limiting accessibility in resource-limited settings.
  • Aptamer-based biosensors offer a promising alternative due to their high specificity, stability, and cost-effectiveness.

Purpose of the Study:

  • To review the recent advancements in aptamer-based sensors for the diagnosis of NCDs.
  • To highlight the potential of aptasensors in point-of-care (POC) diagnostic applications.
  • To discuss the adaptability of these sensors in real-world scenarios and identify future research directions.

Main Methods:

  • Systematic Evolution of Ligands by Exponential Enrichment (SELEX) methodology for aptamer development.
  • Review of electrochemical and optical aptasensor technologies.
  • Analysis of aptasensor performance for various NCD biomarkers.

Main Results:

  • Aptamers exhibit high-affinity binding to diverse NCD-related targets, including proteins and cells.
  • Electrochemical and optical aptasensors demonstrate enhanced sensitivity, selectivity, and stability for disease detection.
  • Applications span across various NCDs such as lung cancer, leukemia, diabetes, and chronic respiratory disorders.

Conclusions:

  • Aptamer-based biosensors are a viable and advanced technology for the early and efficient diagnosis of NCDs.
  • These aptasensors are well-suited for point-of-care diagnostics, offering a practical solution for global health challenges.
  • Further research is needed to overcome current limitations and fully realize the potential of aptasensors in clinical settings.