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Related Experiment Video

Updated: Jun 4, 2025

A Detailed Protocol for Perspiration Monitoring Using a Novel, Small, Wireless Device
05:32

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Hyperbolic-Metamaterial-Based Optical Fiber SPR Sensor Enhanced by a Smart Hydrogel for Perspiration pH Measurements.

Ying Chen1,2,3, Shiqi Hu4,2,3, Chao Shen1,2

  • 1Guangdong Provincial Key Laboratory of Optical Fiber Sensing and Communications, Guangzhou 510632, P. R. China.

Nano Letters
|December 17, 2024
PubMed
Summary

This study presents a novel optical fiber sensor for detecting pH in perspiration using hyperbolic metamaterials and hydrogels. The sensor demonstrates high sensitivity and selectivity for accurate health monitoring.

Keywords:
hydrogelhyperbolic metamaterialsoptical fiber sensorspH sensorsperspirationsurface plasmon resonance

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Area of Science:

  • Optoelectronics
  • Biomedical Engineering
  • Materials Science

Background:

  • Accurate pH monitoring in perspiration is crucial for health diagnostics.
  • Traditional optical fiber sensors face limitations in sensitivity and structural adaptability.
  • Hyperbolic metamaterials (HMMs) offer tunable optical properties for enhanced sensing.

Purpose of the Study:

  • To develop an optical fiber surface plasmon resonance (SPR) sensor for precise pH detection in perspiration.
  • To leverage HMMs and pH-sensitive hydrogels to overcome sensor limitations and improve performance.
  • To evaluate the sensor's sensitivity, selectivity, and stability for potential health monitoring applications.

Main Methods:

  • Fabrication of an optical fiber SPR sensor incorporating dispersion-tunable HMMs.
  • Integration of pH-sensitive hydrogels that exhibit volume changes with pH variations.
  • Characterization of the sensor's refractive index (RI) and pH sensitivity using controlled experiments.
  • Assessment of sensor selectivity against other perspiration constituents (urea, NaCl, glucose).

Main Results:

  • The sensor achieved a high RI sensitivity of 6963.64 nm RIU-1.
  • Demonstrated remarkable pH sensitivities of -64.04 nm pH-1 (pH 2.7-4.7) and -30.63 nm pH-1 (pH 4.7-7.5).
  • Exhibited exceptional pH selectivity over urea, sodium chloride, and glucose, with good operational and storage stability.

Conclusions:

  • The developed HMM-based optical fiber SPR sensor offers a promising platform for accurate and selective perspiration pH detection.
  • The sensor's high sensitivity and stability suggest significant potential for non-invasive health monitoring and medical diagnostics.
  • This technology could advance personalized medicine and disease management through continuous physiological parameter tracking.