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Updated: Jun 4, 2025

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Pyridine-oriented transannular C-H functionalization of arenes

Yanchun Hou1, Jianwei Liu1, Yi Tian1

  • 1School of Chemistry and Chemical Engineering, Chongqing University, 174 Shazheng Street, Chongqing, 400044, China. libs@cqu.edu.cn.

Chemical Communications (Cambridge, England)
|December 18, 2024
PubMed
Summary

A novel pyridine-oriented Friedel-Crafts alkylation reaction creates fused seven- or eight-membered rings. These structures are valuable precursors for pharmaceuticals and other complex molecules.

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