Histoplasmosis Associated With Bat Guano Exposure in Cannabis Growers: 2 Cases
Paulina Sudnik1, Patrick Passarelli1, Angela Branche2
1Department of Infectious Diseases, University of Rochester, Rochester, New York, USA.
Abstract:
Histoplasma capsulatum is a pathogenic dimorphic fungus with evolving epidemiology. Initially described as endemic to the Ohio and Mississippi river valleys, the infection now regularly occurs in central and eastern United States, with cases reported across the entire country. Transmission happens via inhalation of conidia during activities that disturb fungal hyphae. Sporadic cases related to individual exposures now outnumber work-related outbreak cases in the United States. We describe 2 fatal cases of histoplasmosis in Rochester, New York, associated with exposure to bat guano as a fertilizer for cannabis cultivation, including 1 case in which it was commercially obtained.
Insights
Two fatal histoplasmosis cases in New York were linked to inhaling Histoplasma capsulatum spores from bat guano fertilizer used in cannabis cultivation. This highlights evolving transmission routes for this fungal infection.
Area of Science:
- Mycology
- Infectious Diseases
- Epidemiology
Background:
- Histoplasma capsulatum is a dimorphic fungus causing histoplasmosis.
- Historically endemic to specific US regions, its epidemiology is evolving.
- Transmission occurs through inhaling fungal spores (conidia).
More Related Videos
09:57Passive Administration of Monoclonal Antibodies Against H. capsulatum and Others Fungal Pathogens
Published on: February 14, 2011
06:49Reduced Itraconazole Concentration and Durations Are Successful in Treating Batrachochytrium dendrobatidis Infection in Amphibians
Published on: March 14, 2014
Related Concept Videos
01:28Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
01:29Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...