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Negative pressure pulmonary edema: a case report and literature review
Jian Wu1, Hua Yuan1, Zhiqiang Guo1
1Department of Emergency Medicine, Affiliated Kunshan Hospital of Jiangsu University, Kunshan, China.
Abstract:
Negative pressure pulmonary edema (NPPE) is a form of non-cardiogenic pulmonary edema triggered by a swift increase in negative intrapleural pressure due to upper airway obstruction and represents a potential cause of acute respiratory failure. This study documents a case of NPPE post-endotracheal extubation subsequent to general anesthesia. The patient, a young female, underwent a "laparoscopy-assisted unilateral salpingectomy" under general anesthesia for an ectopic pregnancy. Immediately post-extubation, the patient exhibited a sudden decline in oxygen saturation and tachypnea. Pink frothy secretions were suctioned from the oral and nasal cavities. Swift interventions, including oxygen therapy, non-invasive ventilation, diuretics, and corticosteroids, were administered. The patient's condition was effectively managed, and after 6 days of treatment, she was discharged from the hospital following full recovery.
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