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Identifying biomarkers to predict immune-checkpoint therapy response-is it a reality or a distant dream?

Prashanth Ashok Kumar1,2

  • 1George Washington University (GWU) Hospital Medical Faculty Associates, Washington, DC, USA.

Translational Cancer Research
|December 19, 2024
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Immune checkpoint therapygenomic alterationsimmunotherapy resistancenon-small cell lung cancer (NSCLC)predictive biomarkers

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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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