SEASONAL VARIATION OF BLOOD ANALYTES ASSOCIATED WITH SKIN HEALTH IN ALASKAN ICE SEALS

Recent unusual mortality events involving skin pathology in bearded (Erignathus barbatus), ringed (Pusa hispida), and spotted seals (Phoca largha) in Alaska highlight the potential sensitivity of ice-associated species to the complex effects of climate change. The regulation of thyroid hormones, cortisol, and vitamin A have been shown to play essential roles in skin health and seasonal molt in some pinnipeds. Unfortunately, the lack of available reference data for healthy Alaskan ice seals has prevented the adequate evaluation of these factors in cases associated with mortality events. To improve understanding of blood analytes that may serve as useful markers of skin health, we compiled diagnostic information for individuals in long-term managed care following short-term rehabilitation. Thyroid hormones (TT4, TT3, and FT4d), cortisol, and vitamin A levels are reported for four ringed seals, four spotted seals, and three bearded seals at the Alaska SeaLife Center in Seward, Alaska, with serial samples obtained when possible and referenced to time of year. For ringed and spotted seals, the thyroid hormones and vitamin A showed a strong seasonal pattern with peak values obtained during the annual molt in spring, whereas cortisol values did not vary predictably between molting and non-molting periods. Trends were similar for individuals across both sex and species. Bearded seals had fewer available data for younger individuals only, but observed analyte values are provided for this understudied species. Collectively, these measurements can be used to support veterinary management of ice seals under human care and to provide initial baselines for skin health monitoring in wild populations and in stranded individuals with known skin lesions or pathology.