Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Cancer01:30

Skin Cancer

3.1K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
3.1K
Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

13.0K
Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
13.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma: Part 2. Treatment - update 2026.

European journal of cancer (Oxford, England : 1990)·2026
Same author

European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma. Part 1: Diagnostics and prevention - Update 2026.

European journal of cancer (Oxford, England : 1990)·2026
Same author

Perspectives on Artificial Intelligence in Dermatology: An International Cross-Sectional Study.

Medicina (Kaunas, Lithuania)·2026
Same author

A Risk-Scoring Classifier for the Diagnosis and Management of Atypical Melanocytic Lesions of the Palms: the iDScore_palmar Model.

Dermatology practical & conceptual·2026
Same author

Clinical, Dermatoscopic, Histological and Molecular Prognostic and Predictive Factors of Metastatic Melanoma Response to Immunotherapy: A Systematic Review and Drug Class Meta-Analysis.

Journal of clinical medicine·2026
Same author

Comparative and complementary diagnostic value of dermatoscopy and clinical close-up photography in skin cancer diagnosis: A study from the MILK10k dataset.

Journal of the American Academy of Dermatology·2026

Related Experiment Video

Updated: Jun 4, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.2K

European consensus-based interdisciplinary guideline for melanoma. Part 1: Diagnostics - Update 2024.

Claus Garbe1, Teresa Amaral1, Ketty Peris2

  • 1Center for Dermatooncology, Department of Dermatology, Eberhard Karls University, Tuebingen, Germany.

European Journal of Cancer (Oxford, England : 1990)
|December 19, 2024
PubMed
Summary
This summary is machine-generated.

This guideline provides recommendations for diagnosing and treating cutaneous melanoma (CM), the deadliest skin cancer. Early detection via dermoscopy and histopathology, alongside stage-based imaging and mutation testing, improves patient outcomes and relapse monitoring.

Keywords:
AJCC classificationConfocal reflectance microscopyCutaneous melanomaDermatoscopyFollow-up examinationsImaging diagnosticsMutation testingPrimary diagnosisSequential digital dermatoscopyTotal body photography

More Related Videos

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

2.4K
A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

15.7K

Related Experiment Videos

Last Updated: Jun 4, 2025

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
09:37

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition

Published on: August 18, 2022

2.2K
A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
07:41

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis

Published on: March 8, 2022

2.4K
A 3D Organotypic Melanoma Spheroid Skin Model
08:49

A 3D Organotypic Melanoma Spheroid Skin Model

Published on: May 18, 2018

15.7K

Area of Science:

  • Dermatology
  • Oncology
  • Medical Guidelines

Background:

  • Cutaneous melanoma (CM) is the most dangerous skin tumor, causing 90% of skin cancer deaths.
  • Accurate diagnosis and treatment are crucial for improving patient survival rates.

Purpose of the Study:

  • To provide evidence-based recommendations for the diagnosis and treatment of melanoma.
  • To establish a structured follow-up regimen for early detection of relapses and secondary primary melanomas.

Main Methods:

  • Systematic literature research and consensus conferences involving multidisciplinary experts.
  • Development of a stage-based diagnostic and treatment guideline, including imaging and mutation testing recommendations.

Main Results:

  • Melanoma diagnosis requires clinical evaluation, dermoscopy, and histopathological confirmation.
  • Diagnostic imaging and mutation testing (e.g., BRAF V600) are recommended based on melanoma stage (from IB/IIB/C).
  • A structured, stage-based follow-up regimen is proposed for optimal patient monitoring.

Conclusions:

  • Adherence to these guidelines can enhance early melanoma detection and management.
  • The guideline emphasizes the importance of a multidisciplinary approach and structured follow-up for melanoma patients.
  • This guideline is valid until the end of 2026, promoting current best practices in melanoma care.