Related Experiment Video
Updated: May 14, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
Prevalence and Risk Factors of Poststroke Cognitive Impairment: A Systematic Review and Meta-Analysis
Yuxia Ma1,2, Yifang Yang1, Xinyu Wang3
1School of Nursing, Evidence-Based Nursing Center, Lanzhou University, Lanzhou, China.
Background:
Stroke is a common disease that poses a significant threat to human health. Approximately one-third of stroke patients experience poststroke cognitive impairment (PSCI), which severely impacts their quality of life and survival time. Although the prevalence and risk factors for PSCI have been widely reported, these results have not been synthesized.
Objectives:
This systematic review was conducted to explore the prevalence and risk factors of PSCI.
Methods:
PubMed, EMBASE, Web of Science, and Cochrane Library were comprehensively searched for studies exploring the prevalence and risk factors of PSCI from inception to July 5, 2022.
Results:
A total of 49 articles were included for meta-analysis. It was found that the combined prevalence of PSCI was 39%-47%. Risk factors for PSCI include female gender, age, education level less than 7 years, atrial fibrillation, diabetes, smoking, drinking, hypertension, coronary artery disease, carotid artery plaque, admission NIHSS score ≥ 5, unemployment, and homocysteine.
Conclusions:
This systematic review has revealed a combined prevalence of PSCI is ranging from 39% to 47% and identified several risk factors for PSCI. These findings indicate a high incidence of the condition and underscore the need for increased public awareness. Future investigations should prioritize the identification of PSCI risk factors, providing a theoretical basis for nursing professionals to effectively manage and treat PSCI patients.
Related Concept Videos
Stroke: Introduction and Types
Ischemic Stroke l: Introduction
Ischemic Stroke ll: Pathophysiology
Hemorrhagic Stroke ll: Pathophysiology
Alzheimer Disease l: Introduction
Dementia l: Introduction

