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The need for analgesic cover after ENT surgery--comparison of nefopam and papaveretum
Insights
Papaveretum and nefopam were compared for smooth emergence from ENT anesthesia in children. Papaveretum showed higher satisfaction, while nefopam offered a useful alternative due to no respiratory depression.
Area of Science:
- Pediatric Anesthesiology
- Pharmacology
Background:
- Smooth emergence from anesthesia is critical for pediatric patients undergoing ENT surgery.
- Current anesthetic emergence strategies require evaluation for efficacy and safety.
Purpose of the Study:
- To compare the efficacy of papaveretum and nefopam for promoting smooth emergence from ENT anesthesia in children.
- To assess the safety profile, particularly respiratory depression, of both agents.
Main Methods:
- A consecutive series of 40 children undergoing ENT anesthesia were alternately administered intramuscular papaveretum (0.3 mg/kg) or nefopam (0.4 mg/kg).
- Emergence was observed and assessed for satisfaction over 30 minutes post-surgery.
Main Results:
- Satisfactory emergence was achieved in 19/20 children receiving papaveretum.
- Satisfactory emergence was achieved in 15/20 children receiving nefopam.
- Nefopam did not cause respiratory depression, unlike some other agents.
Conclusions:
- Papaveretum is effective and popular for smooth emergence in pediatric ENT surgery.
- Nefopam serves as a valuable alternative, especially for its lack of respiratory depression.
- This study represents the first report on nefopam use in pediatric patients for anesthetic emergence.
Abstract:
Intra-operative intramuscular injections of either papaveretum 0.3 mg/kg or nefopam 0.4 mg/kg were given to alternate patients to promote smooth emergence from ENT anaesthesia in a consecutive series of 40 children. Observations over a period of 30 minutes following completion of surgery showed that emergence was satisfactory in 19 out of 20 children given papaveretum, and in 15 out of 20 children given nefopam. The study confirms that this indication for papaveretum is justifiably popular and that nefopam is a useful alternative mainly because it does not cause respiratory depression. There are no previous reports of the use of nefopam in children.