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Case report: HSV lymphadenitis in immunocompromised patient with CLL
Talal Al-Assil1, Shane Handelsman1, Faisal Ansari2
1Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, MI, United States.
Chronic lymphocytic leukemia (CLL) patients with lymphadenopathy may have herpes simplex virus (HSV) lymphadenitis, not Richter's transformation. Prompt diagnosis and antiviral therapy are crucial for managing this infection and CLL recurrence.
Area of Science:
- Hematology
- Oncology
- Infectious Diseases
Background:
- Chronic lymphocytic leukemia (CLL) patients experience immune dysregulation, increasing susceptibility to severe infections.
- Richter's transformation (RT) in CLL is a poor prognostic indicator requiring immediate treatment adjustments.
- CLL patients undergoing immunosuppressive therapies are at higher risk for opportunistic infections.
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